Here are some of our favorite stars that played roles as or alongside doctors on the screen.. only one however is a real doctor:

Penélope Cruz
Penélope Cruz Sánchez, known professionally as Penélope Cruz, is a Spanish actress and model. Signed by an agent at age 15, she made her acting debut at 16 on television and her feature film debut at 16 on television and her feature film debut the following year in Jamón, jamón (1992) to critical acclaim.

Michael C. Hall
Michael Carlyle Hall is an American actor, known for his role as Dexter Morgan, a blood spatter analyst, in the Showtime TV Network series, Dexter, and as David Fisher in the HBO drama series, Six Feet Under.
Amber Heard

Amber Laura Heard is an American actress. Heard made her film debut in the sports drama Friday Night Lights, starring Billy Bob Thornton.
Johnny Depp

John Christopher “Johnny” Depp II is an American actor, producer, and musician. He has won the Golden Globe Award and Screen Actors Guild Award for Best Actor.

Agnes Bruckner
Agnes Bruckner is an American actress and former photomodell. She began acting on television in the late 1990s and has since appeared in several films, including The Woods, Blue Car, Murder By Numbers, Blood and Chocolate, and The Anna Nicole Story.

Megan Fox
Megan Denise Fox is an American actress and model. She began her acting career in 2001, with several minor television and film roles, and played a regular role on the Hope & Faith television sitcom.

Ellen DeGeneres
Ellen Lee DeGeneres is an American comedian, television host, actress, writer, and producer. She starred in the popular sitcom Ellen from 1994 to 1998, and has hosted her syndicated TV talk show, The Ellen DeGeneres Show, since 2003.

Scarlett Johansson
Scarlett Johansson is an American actress, model, and singer. She made her film debut in North. Johansson subsequently starred in Manny & Lo in 1996, and garnered further acclaim and prominence with roles in The Horse Whisperer and Ghost World.

Reese Witherspoon
Laura Jeanne Reese Witherspoon, known professionally as Reese Witherspoon, is an American actress and producer.

Cameron Diaz
Cameron Michelle Diaz is an American actress, producer, and former fashion model. She rose to stardom with roles in The Mask, My Best Friend’s Wedding and There’s Something About Mary.

Mehmet Oz
Mehmet Cengiz Öz, better known as Dr. Oz, is a Turkish-American cardiothoracic surgeon, author and television personality.