My daughter is 12 yrs old she is suffering since 1.5 year from abdominal pain in LRQ with vomiting ,joints pain , rashes on legs ,mouth ulcers , rebound tenderness localized in iliac fossa. symptoms disappear for nearly one week then returned appendectomy was done without any change in symptoms. CT,Abdomen U/S, MRI,Colonoscopy ,blood tests ,urine analysis ,stool analysis are normal. Paediatric Gastroenterologist diagnosed as FMF but the gene test was negative no response on colchicine 2mg/day