Is it safe to take Mirtazapine 30ml, Aripiprazole 5ml and Sertraline 50ml per day at the same time? My father-in-law is taking them and he’s changed, he’s gone silent, gained weight and doesn’t eat properly.

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Is it safe to take Mirtazapine 30ml, Aripiprazole 5ml and Sertraline 50ml per day at the same time? My father-in-law is taking them and he’s changed, he’s gone silent, gained weight and doesn’t eat properly.

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hi
Mirtazapine and Sertraline have synergistic effects on the nervous system. They act almost in the same way and have similar effects on the body. It would be better if he takes only either of them. However,before stopping any drug,he should consult with a psychiatrist to avoid withdrawal effects.
Thanks
HI
THESE DRUGS CAN BE TAKEN SAFELY TOGETHER ALTHOUGH THE DOSE SEEMS TO BE A LITTLE HIGHER THAN THE EXPECTED THERAUPEUTIC RECOMMENDATIONS. TRY AND REDUCE THE DOSES TO GET THE OPTIMUM RESULTS
hello there
he can take them quite safely. getting silent can be due to additive effect of the medicines. He should take the medicines with atleast 3 hours interval between two tablets. other symptoms that you have mentioned do not seem to be related to the drug combination