My Husband has decompensated liver disease, what is the prognosis?

My Husband has decompensated liver disease. He was first diagnosed in August 2015. He has had several variceal bleeds, jaundice, ascites, hepatic encatholopothy and a range of other issues. He spent one month in the ICU in 2016 and nearly died multiple times. He had a TIPS operation in December 2016 after which no he has visible ascites, no bleeds but some HE, weakness, muscle wastage and jaundice. He stills drinks, though is currently 1 week sober, what is the best prognosis? What is the likely prognosis?

Age: 40
Medications: Nobe
General Information: Husband is 43, takes vitamins incl thiamin and iron but not much else. Also, barely eats.

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2 Answers on "My Husband has decompensated liver disease, what is the prognosis?"

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Dr. Deepak Patel
Dr. Deepak Patel

Hello. Unfortunately decompensated liver disease prognosis is not very good. In my opinion, it would range from a few months to a couple of years. After TIPS the average statistical survival rate at three, six, 12, and 18 months is of 81%, 71%, 48%, and 35%, respectively.


Decompensated liver disease with bleeding varices, ascites, jaundice and other conditions along with still intake of alcohol makes the condition further worsening and in such cases the survival rate further falls to less than an year in more than fifty percent of patients..

In such patients if other parameters are within limited range like functioning of heart, kidneys etc and alcohol intake is completely stopped then Liver transplant can be an option..

So you should look for options like Liver transplant with a positive hope of improvement.

Please keep posted.