How to treat leiomyosarcoma and rectal cancer at the same time?

Hi,
My 54 year old wife had been battling stage 4 leiomyosarcoma for the past 10 years. She has tumors in about 8 locations, lung, stomach, limbs, bone. It has been slowly advancing and is chemo resistant. Now if you can believe it she has rectal cancer with invasive adenocarcinoma. It was removed w/o clear margins through TAE. It was 5 CM, poorly differentiated cells, invaded perirectal tissue, invaded perineural, and has suspected lymphovascular invasion. How in the heck does she attack both at one time. TY